Luminescence and Preventive Effect of Two New Cd(II) Compounds on Scar Formation after Cosmetic Surgery

Two coordination polymers involving Cd(II), i.e., [Cd2(IDPA)2(bpe) (H2O)2]n·2n(H2O) (1) (H2IDPA is 5-(1-oxoisoindolin-2-yl)isophthalic acid, bpe 1,2-bis(4-pyridyl)ethane, 4-bpmh N, N-bis-pyridin-4-ylmethylene-hydrazine), and [Cd(IDPA)(4-bpmh)0.5(H2O)2]n·n(H2O) (2) are prepared under solvothermal conditions via tuning the auxiliary ligand from to 4-bpmh. Moreover, as-prepared complexes 1–2 reveal much stronger luminescence in contrast that of free organic ligands. Their preventive effect mechanism on scar formation after cosmetic surgery was explored. First, two complexes’ suppression viability human immortal keratinocyte line (HaCaT) cell examined exploiting counting kit-8 (CCK-8) detection. The vascular endothelial growth factor (VEGF) signal pathway activation HaCaT cells detected by real-time reverse transcription-polymerase chain reaction (RT-PCR) assay.